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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a329ff3ba57fa457973d019bda891fabb2b2f9d41caca1cfef6ccd14f155d3b1' 
  AND token = 'SMUl8smu2WnnF8uyYBzmBBLnLmfAmf7y50rb6fWyl/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}