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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef8e6dee1ea65eb12dd94ce8bfff04e83337b2569a4da57ade50bfd2e232afc' 
  AND token = 'EDcOVezAVXmtvv82pKv4PXeAWLpZYRNfOCSO6PAsMeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}