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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad653f381636f6c3f6906befc8f45efdb733c887c78c2ba449dd959e55a55c4c' 
  AND token = 'hnEw3GiwcZEkS28UdPHp0CQ0+ujdFrMk1ZzB4pEEHbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}