SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7176b06b18cd345dbd23cae229cb4e6dad49e043a070f731090c46243c4552' 
  AND token = 'J67o1jwwXmS5L9LXGQ/PGC6iW+e2OGbG7Uo9arXMq9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}