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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0eb87b3d5447b1ca4ad49b760627450c73c504aa08b5e3eef9c06e95691637' 
  AND token = '21OsB9Z4HZkSiiraKm/f3IlXHsF8CrW86U9WSQ3YRCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}