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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a71b1ea4de6d69c215cf091bc1d4898402898bfe9224e48e052361ff94c46b' 
  AND token = 'djbtbA/lNkUgr2D7YWxiy7B70+0OuCR1bu6Cn7MXDbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}