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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '473022cd3619ace05f8d7ec0974998bc32b5e5a68e32254bc01423178946f0c8' 
  AND token = '6A++SFCm7IzvZtlkiMvesO5QM6HcYl2zSiCmI2MPzqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}