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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1611364bd8a014c272a45418150be46083b4e4d0a4224c60df9bd2f6b2ab5cb9' 
  AND token = '27fC3p49OPziFLFp0ky/PPGxPd58z5OkW/JDVTrOKiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}