SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c39b7721c5a613bfc8c67791616c80ff3cff6b1b0b628eabd782be343c7884' 
  AND token = 'Icu5Hy9xs52JI1vOfQKniiTD8ojRuzyzHjR6V06XHO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}