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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0c86e75e2e694e2ce8bc6d9ce4eb2d31b96060bf379ecf73c35e754fda7d36' 
  AND token = 'hitnPcUNUAjGX5dpTm//mpANYZMMrCGxWO83TdO7m9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}