SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41ebe3b5aac0a269341718f4eaa80b7cecfa81558463d1b197b4718b9e609cd' 
  AND token = '8P8yxrtSi34OCFz5uwwkz9g3DUvs+bx+yr1bjKrR+5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}