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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e6dbd944d94c78b0280949a10688ea3853636a8fa348cca8114f505fdacd20' 
  AND token = 'HYBULC5OXZlkaLHargN2u3aRpzsHJWGZPiFR+WXVmEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}