SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c225a7e955b4f38dd18c80d20c39595dc24b5b617127da16243acd764894b0b' 
  AND token = 'GTdF0Ay52o9efY1YrKFczT7ItX5HLzWLlG+JEw6IMRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}