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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6caadfc1089834ec2390f824e468bbc225657b3d9f0d56e2c34eb303ce4b0dbf' 
  AND token = 'S787TyLymKgcjMSvHImDvKW9ZDRHiwojnWU/Kb6S4DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}