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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4530f8bf3db65976d1abe38da6dd2485a0b121ecd42c38a188f0352df1cb6c51' 
  AND token = 'MvD+dW210HftRrXn+buJrifWX2vOqHpRa8ZcrU1uB5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}