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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a438fe70bf0e22275b63b9be5e9cb1beeb85e08aa18a52025d4dc87979aa505e' 
  AND token = 'pWmrm2gDZBD7yz3UeLsZL1ekX6QgRpUAhoh5JW3LrzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}