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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65ec06e086c9f849e87045b6e30ff6f5dfe93c0141167784c86ff2baae33751' 
  AND token = 'Lw55CbFPMXIPEegzQGN7HFt4E0plmUBZhxon/qPMkwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}