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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b43c325336f962d9f067ba31d9a12e9266bf46d62398db4088fbf3b0bec9ab0' 
  AND token = 'Mr3NhhRn0W1++qjibFdMdHPD93NLIHzF9xqqV8esTyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}