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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8c3aea25bad47c47b2a5a4d4726d34de7bb897f8423199cf4fd6ef57bef16c' 
  AND token = 'zu6mLRQBP0w4vAv/A0dOwp8MbIkz/2n3iD2MMr+JHgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}