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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f76e96f6d25976d6aa835a67e5a2a91a2618c35ea03fd017b684d0a98c2fc11' 
  AND token = 'sKEM2MpfwuJUVudLLsZiTNVfeOpOAHX3mrEOyFJlZVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}