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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ecd0d642fc7f735d5d6505a77c30fb2e1a9bb45e7d9fd327eaecc0f5be9b986' 
  AND token = 'GyIPm2wK0DoV/G8cWgWvURxcfbA/w3jcRvXIvWzCEy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}