SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489f5b93b7c4886f8eb578475dbbed3411686d6a20ed540e311201148e006eb4' 
  AND token = '+/NQQ9gsnwCmOqUCVj/W1Z5ZvvJTWID5WfLpDzewWcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}