SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea12d17011bff1c27d6e741ab3a9c8b349595d851e4c8a49dcfddb357abe2ce' 
  AND token = 'GDgKn/GyW3SP149+S32OeD2YI6dOUpT8l2ohIIJxOes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}