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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb1d9ded062ecf9d419ffa5cad2d00de2947f167f8bbdc6178ee91e21d1bcde5' 
  AND token = 'eDeKv1NOzA+0DEyX0tRcR6hIEt+6OfZMYTeOcITfLig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}