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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5563cf365c93b2da672b2c96fb95c9e4200a6816e526ce1ee64b3671996f71a' 
  AND token = 'F/XIMWyfWSowyhxMQR5XOci+5W9U/iq9WKUvCoAPyuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}