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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404d6d2170c02b472a17a7fdef1237eb867289f98c94e08d9c043f262f501f28' 
  AND token = 'pvHWMFP1Afb5JcvoGwR0B41h5YXH4ERf+9qaYe/lDo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}