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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c268f5e30f8a426e3489278639626dc057d0c9a22c825e18b6c66b7e2c1bff' 
  AND token = 'T3eoAAoOYxckRu4R5uGl5JuINQJjWAsGvmdrGGc6eK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}