SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745253882ec1338c56aadecf8aaf10ce2c891453a72f6aad55465b12d087b7d4' 
  AND token = '3EhNBbpA6t9RmuBgsFYMkQHlTs0uaWDx8S9CmNGMcR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}