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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404f843394b53cb5ba8af8bd94f213c5c59aca02ba9e2a2dcf82c8fc00f1757b' 
  AND token = 'fOuhjhUqjsEQ3Yl7wPZURRMHyAiXrZRLUR9sfNNpps8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}