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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c431df899d603ee328d4ce4569a00a098f0fbb7ec7a1d37e91c8eb1a1715368d' 
  AND token = '9VzkLGlxuxbN1AR5WL7GsQlQh2MiiONcOGqPQ8hP0rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}