SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcb1be21697d2183b9a3c608e9113db6459e22ba52f52e65509c754e46cdd1c7' 
  AND token = 'USZ9f8KoIffENIWe/yIlfM2gmyg+YjyhZUCiOZbY3PU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}