SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42aefd6f915d1e2f88e9244f76d56af582d0c3101261a83fbb99128e218c17e6' 
  AND token = 'lXjjQgUc+vP6U7csgMkyxzAiep1aydhsESAn77lS4J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}