SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '608ffeb5838edf3d1cb54e4a23b8bc72914695b20259db85c8406c1c4d85b171' 
  AND token = 'CMCaTxjFAKz8Ov1bMXc0PXjBEXjBw9wO8Me2h/vb1sE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}