SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a94829a59bbdd763af893a15d2c3c6fac826a83c3e1a39ea9dd6e64435dac4' 
  AND token = 'FrB8+jWJjOb9PrizEIUAFAi+jIkBJvjqPQiRB+3gC0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}