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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0763434ac3a30151c95df9f319c3a4bf5649ad22cb0f170e7d4eaf601d2e401' 
  AND token = 'Dl0BsDtsVeNM9nZrMz2kW4MwQ2zEztc0SSga1IWy0K8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}