SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6acad7583108013fe872afc4022639ad815cde8dab5fe43ddb69e539173e8d5' 
  AND token = 'di2YPpvUj3k5iD+d9uBOBeZwDek3FX3sFRLnnSkO5Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}