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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6adc3f2f364819727ea2d9feb6f2bd94a997f1842ac2ed6664cf0ca882ec69' 
  AND token = 'BsJUt87cfTckW20UTB7jyco2CceC7lBftTImvRKWocU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}