SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4403c69acfdf609ffc9d4f6de01f0f37f36f2ad2937205ab3886e0e8c768fe2b' 
  AND token = 'J7HfYu43dkXaaLnStAD4gYs/wzhejpvcDRlmAkQzKy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}