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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54819379d72594b7a72f5ed345416bf363b82808762be167990776b1aaaa66fc' 
  AND token = '42NwGwFf96GogkUyS78if4I/xG7nVr33M+k+3fS5PLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}