SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c464314175be7f6025f265015082287e07c354b2ac5136805830e994151224' 
  AND token = '9Pj8qeZke7eWw/EwnZOsN+Dx1IPHhK649RWpYbW01xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}