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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c27fe793079cb048ae03586c36ab4552c1d21d75c02eb3cfe6cb062023a4ca2' 
  AND token = 'UF27GXBLvlrD+2YXaEMJMp5pKvBKxXpPySYj1xFdrzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}