SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10afd3d4fa1af8e81d332ccf1e8ee1d4274ceec1bd9d48290d5899a93a243da6' 
  AND token = 'ETe742NBhP3ZOFePMzLbEQn2F7jZ7aBtU6wB4DIIYrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}