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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1980f22bf4be0df437a759fec859630bd8c246fa060c0dbaccc0343c3008f974' 
  AND token = 'zeS5RcMZR/dcqFX/RbuqLRZVnNS7CSJm+PHDOYbh9wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}