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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e139ae33786f25a487038f399298eab7f71cb50a935e042200853248a3af8400' 
  AND token = 'M/Nmf/nG7ftyZMM2pKeKgJpI3xgTgYZ0PZTDOvJfRLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}