SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38be304cc6c4ee7c3a0b7402b22748b753383c234405efff51ad005a42ec1440' 
  AND token = 'NPCudG1X0t+/0Rh29bM+3raiiIhhdgEySQ+2IZ0wTTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}