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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50e4e9e66f20cc089452c8d0be9518448a70b435f421af6f24294d8e79c26f6' 
  AND token = 'bVx325ZFdrRnzYGcccIS5gcvtUR1b/lmfQSqKzdxfM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}