SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33501ebe6fb73055f4acd7c91e1bb928eb937753f98d68d5bab74e4dbe61b81' 
  AND token = 'qHUahC2Equj8jM8n42UdktpS7JgG4NtQ3smxlE1Ox3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}