SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0d01294cbb308d73af8053765913ac82482640833d6b762d70370a20520238' 
  AND token = 'syrZkT318mnzZwqzHfYUeu+T/c+p5xKGkkrVdwb4ae0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}