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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ad672f0d7511940aa41ab4b298b5a1f071a0f5d2c1e56bd4ee5c3383043a78' 
  AND token = 'PaDYUmu9LG/UaVpcW0qTZokCOSFamGyy4g+WB2Ch07Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}