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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df81277e600edeacf500fe2f1f426e304f3bf3d99c04abccb060ec481e6ee88' 
  AND token = '6NwsRN7KnQgzLq/B5UhQnW90iD8QD0+p0pYIk2sCWEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}